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74844-91-0 N-Boc-trans-4-Hydroxy-L-proline Methyl Ester

74844-91-0 N-Boc-trans-4-Hydroxy-L-proline Methyl Ester

N-Boc-trans-4-Hydroxy-L-proline methyl ester Basic information N-Boc-trans-4-Hydroxy-L-proline methyl ester Chemical Properties Safety Information MSDS Information N-Boc-trans-4-Hydroxy-L-proline methyl ester Usage And Synthesis N-Boc-trans-4-Hydroxy-L-proline methyl ester Preparation Products...

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Product Details:

N-Boc-trans-4-Hydroxy-L-proline methyl ester Basic information

Product Name:

N-Boc-trans-4-Hydroxy-L-proline methyl ester

Synonyms:

N-T-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER; N- (TERT-BUTOXYCARBONYL) -TRANS-HYDROXYL-L-PROLINE METHYL ESTER; N-ALPHA-T-BUTOXYCARBONYL-L-HYDROXYPROLINE METHYL ESTER; N-BOC-TRANS-4-HYDROXYL-L-PROLINE METHYL ESTER; N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER; N-BOC-4-HYDROXY-L-PROLINE METHYL ESTER; N-BOC-L-TRANS-4-HYDROXY-PROLINE METHYL ESTER; (2R,4R) -4-HYDROXY-PYRROLIDINE-1, 2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER

CAS:

74844-91-0

MF:

C11H19NO5

MW:

245.27

EINECS:

1592732-453-0

Product Categories:

Amino Acids and Derivatives; Hydroxyproline [Hyp]; Unusual Amino Acids; Amino   Acids 13C, 2H, 15N; Boc-Amino acid series; Amino Acids & Derivatives; Heterocycles; Peptide Synthesis; Proline Derivatives; Unnatural Amino Acid Derivatives

Mol File:

74844-91-0.mol

image001_副本.jpg


N-Boc-trans-4-Hydroxy-L-proline methyl ester Chemical Properties

Melting point

92-96 °C(lit.)

alpha

-65 º (c=1 CHCl3)

Boiling point

132°C/0.05mmHg(lit.)

storage temp.

2-8°C

solubility

Soluble in chloroform, dichloromethane and ethyl acetate.

form

Crystalline Powder

color

White to light beige

CAS DataBase Reference

74844-91-0(CAS DataBase Reference)


Safety Information

Hazard Codes

Xn

Risk Statements

20/21/22-36/37/38

Safety Statements

24/25-36-26

WGK Germany

3

HazardClass

IRRITANT

HS Code

29339900


MSDS Information


N-Boc-trans-4-Hydroxy-L-proline methyl ester Usage And   Synthesis

Chemical Properties

Clear Colourless Oil

Uses

A potential iNOS inhibitor.

Uses

(2S, 4R) -4-Hydroxypyrrolidine-1, 2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester roline scaffold.


N-Boc-trans-4-Hydroxy-L-proline methyl ester Preparation Products And Raw materials


Upstream information

(2S, 4R) -Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride; benzoic acid; Diisopropyl azodicarboxylate; Triphenylphosphine; methanesulfonic acid; sodium carbonate; sodium hydrogencarbonate; Methanesulfonyl chloride; diazomethyl (trimethyl) silane; p-Toluenesulfonyl chloride;


Downtream information

(2S, 4R) -4-Azido-1,2-pyrrolidinedicarboxylic Acid 1- (1, 1-Dimethylethyl) 2-Methyl Ester; 1-O-tert-butyl 2-O-methyl (2S, 4S) -4-naphthalen-2-yloxypyrrolidine-1,2-dicarboxylate; 1-O-tert-butyl 2-O-methyl (2S, 4S) -4-(4-nitrobenzoyl) oxypyrrolidine-1, 2-dicarboxylate; Boc- (cis-4-N3) Pro-OMe; 1-O-tert-butyl 2-O-methyl (2S) -2, 3-dihydropyrrole-1, 2-dicarboxylate; 1-O-tert-butyl 2-O-methyl (2S) -2, 5-dihydropyrrole-1, 2-dicarboxylate; (1aR, 5S, 8S, 10R, 22aR) -5-tert-butyl-14-methoxy-3 , 6-dioxo-1, 1a, 3, 4, 5, 6, 9, 10, 18, 19, 20, 21, 22, 22a-tetradecahydro-8H-7, 10-methanocyclopropa[18, 19][1, 10, 3, 6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid; N-BOC-cis-4-Hydroxy-L-proline; (2S, 4R)-4-fluoro-1- [ (2-methylpropan-2-yl) oxycarbonyl] pyrrolidine-2-carboxylic acid; (2S, 4S) -1-[(2-methylpropan-2-yl) oxycarbonyl]-4- (trifluoromethyl) pyrrolidine-2-carboxylic acid;


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