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32161-06-1 N-Acetyl-4-piperidone

32161-06-1 N-Acetyl-4-piperidone

N-Acetyl-4-piperidone Basic information N-Acetyl-4-piperidone Chemical Properties Safety Information MSDS Information N-Acetyl-4-piperidone Usage And Synthesi N-Acetyl-4-piperidone Preparation Products And Raw materials Upstream information 1-(4-hydroxy-4-methoxypiperidin-1-yl) ethan-1-one;...

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Product Details:

N-Acetyl-4-piperidone Basic information

Product Name:

N-Acetyl-4-piperidone

Synonyms:

N-ACETYL-4-PIPERIDONE; N-ACETYLPIPERIDIN-4-ONE; AKOS BBS-00004258; 1-ACETYL-4-PIPERIDONE; 1-Acetyl-4-piperidinone; 4-Piperidinone, 1-acetyl-; N-Acetylpiperidone; 1-Acetyl-4-oxopiperidine

CAS:

32161-06-1

MF:

C7H11NO2

MW:

141.17

EINECS:

250-937-6

Product Categories:

PHARMACEUTICAL INTERMEDIATES; Building Blocks; Heterocyclic Building Blocks; Piperidones

Mol File:

32161-06-1.mol

image001_副本.jpg


N-Acetyl-4-piperidone Chemical Properties

Boiling point

218 °C(lit.)

density

1.146 g/mL at 25 °C(lit.)

refractive index

n20/D 1.503(lit.)

Fp

>230 °F

storage temp.

Store below +30°C.

form

Oily Liquid

color

Clear orange

Water Solubility

Soluble in water. Insoluble in acetic acid.

BRN

116031

CAS DataBase Reference

32161-06-1(CAS DataBase Reference)

NIST Chemistry Reference

1-Acetyl-4-piperidone(32161-06-1)


Safety Information

Hazard Codes

Xi

Risk Statements

36/37/38

Safety Statements

23-24/25-36-26

WGK Germany

3

F

10

Hs code

2933399090


MSDS Information


N-Acetyl-4-piperidone Usage And Synthesi

Chemical Properties

clear orange oily liquid

Synthesis route

image003_副本.jpg

Reference:

Alekseyev; Kurkin; Yurovskaya   Chemistry of Heterocyclic Compounds, 2011 , vol. 47, # 5 p. 584 – 596


image005_副本.jpg

Reference:

Zhang, Chengwei; Li, Zhaodong; Zhu, Lin; Yu, Limei; Wang, Zhentao; Li, Chaozhong Journal of the American Chemical Society, 2013 , vol. 135, # 38 p. 14082 – 14085


image007_副本.jpg

Reference:

Kobashi, Seiichi; Kubo, Hajime; Yamauchi, Takayasu; Higashiyama, Kimio Biological and Pharmaceutical Bulletin, 2002 , vol. 25, # 8 p. 1030 – 1034


image009_副本.jpg

Reference:

Biological and Pharmaceutical Bulletin, vol. 25, # 8 p. 1030 - 1034


N-Acetyl-4-piperidone Preparation Products And Raw materials


Upstream information

1-(4-hydroxy-4-methoxypiperidin-1-yl) ethan-1-one; piperidin-4-one; 2, 6-Dimethylphenol; Methyltriphenylphosphonium bromide; 4-Piperidone Hydrochloride Monohydrate; 4-oxopiperidinium chloride; 2-Bromoaniline; morpholine; acetyl chloride; 2-Methyl-1, 2-Propanediamine;


Downtream information

butyl 4-(6-chloro-1,3-benzodioxol-5-yl) -2-methyl-5-oxo-4, 6, 7, 8-tetrahydro-1H-quinoline-3-carboxylate; 1-(4-hydroxyiminopiperidin-1-yl) ethanone; 3-(3-chlorophenyl) -4, 5, 6, 7-tetrahydro-1H-pyrazolo[4,3-c] pyridine; Spiro[chromene-2, 4'-piperidin]-4-(3H)-one; 1-(4-methylidenepiperidin-1-yl)ethanone; 3-(4-Methylphenyl) -4, 5, 6, 7-tetrahydro-1H-pyrazolo[4, 3-c] pyridine; 1-(3, 3-dimethyl-1, 4, 8-triazaspiro[4.5]decan-8-yl) ethanone; 1-(4-morpholin-4-yl-3, 6-dihydro-2H-pyridin-1-yl) ethanone; 4-(4, 5, 6, 7-tetrahydro-1H-pyrazolo[4, 3-c]pyridin-3-yl) benzonitrile; 3-(3, 4-dimethoxyphenyl)-4, 5, 6, 7-tetrahydro-1H-pyrazolo[4, 3-c]pyridine;


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