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657428-42-7 4,6-Dihydro-1h-pyrrolo[3,4-c]pyrazole-5-carboxylic Acid Tert-butyl Ester

657428-42-7 4,6-Dihydro-1h-pyrrolo[3,4-c]pyrazole-5-carboxylic Acid Tert-butyl Ester

Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid, 4,6-dihydro-, 1,1-dimethylethyl ester Basic information Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid,4,6-dihydro-, 1,1-dimethylethyl ester Chemical Properties Safety Information MSDS Information Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid,...

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Product Details:

Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid,   4,6-dihydro-, 1,1-dimethylethyl ester Basic information

Product Name:

Pyrrolo[3, 4-c] pyrazole-5(1H) -carboxylic acid, 4, 6-dihydro-, 1, 1-dimethylethyl ester

Synonyms:

Pyrrolo[3, 4-c] pyrazole-5(1H) -carboxylic acid, 4, 6-dihydro-, 1, 1-dimethylethyl ester; 5-Boc-4, 6-Dihydro-1H-pyrrolo[3, 4-c] pyrazole; 5-Boc-4, 6-Dihydro-1H-pyrr...; tert-butyl 1H, 4H, 5H, 6H-pyrrolo[3, 4-c] pyrazole-5- carboxylate; tert-butyl   4,6-dihydropyrrolo[3, 4-c]pyrazole-5(1H) -carboxylate; N-Boc-pyrazolopyrrolidine;4, 6-Dihydropyrrolo[3, 4-c]pyrazole-5(1H) -carboxylic acid tert-butyl ester; tert-Butyl 4, 6-dihydro-1H-pyrrolo[3, 4-c] pyrazole-5-carboxylate

CAS:

657428-42-7

MF:

C10H15N3O2

MW:

209.245

EINECS:


Product Categories:

Heterocycles   series

Mol File:

657428-42-7.mol

image001_副本.jpg


Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid,4,6-dihydro-, 1,1-dimethylethyl ester Chemical Properties

Density:

1.243g/cm3

Boiling Point:

366ºC at 760 mmHg

Flash Point:

175.2ºC

Refractive Index:

1.563


Safety Information

HS Code:

2933990090


MSDS Information


Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid,   4,6-dihydro-, 1,1-dimethylethyl ester Usage And Synthesis

Description

4, 6-Dihydro-1H-pyrrolo[3, 4-c]pyrazole-5-carboxylic Acid tert-Butyl Ester is an intermediate in the synthesis of Omarigliptin, a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes

Intermediate as

1226781-44-7 Omarigliptin


Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid,   4,6-dihydro-, 1,1-dimethylethyl ester Preparation Products And Raw materials


Upstream information

tert-butyl (3Z) -3-[(dimethylamino) methylene]-4-oxopyrrolidine-1 -carboxylate; N-(tert-Butoxycarbonyl) -3-pyrrolidinone; 2, 4, 5, 6-Tetrahydropyrrolo[3,4-c]pyrazole; 4, 6-Dihydro-1H-pyrrolo[3, 4-c]pyrazole-5-carboxylic acid tert-butyl ester; tert-butoxycarbonyl anhydride;


Downtream information

2, 4, 5, 6-Tetrahydropyrrolo[3, 4-c]pyrazole; Omarigliptin; 4, 6-Dihydro-1H-pyrrolo[3, 4-c]pyrazole-5-carboxylic acid tert-butyl ester;


HNMR

image003.jpg

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