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47173-80-8 N-Boc-O-Benzyl-D-serine

47173-80-8 N-Boc-O-Benzyl-D-serine

N-Boc-O-Benzyl-D-serine Basic information N-Boc-O-Benzyl-D-serine Chemical Properties Safety Information N-Boc-O-Benzyl-D-serine Usage And Synthesis N-Boc-O-Benzyl-D-serine Preparation Products And Raw materials Upstream information N-Boc-O-Benzyl-D-serine; tert-butoxycarbonyl anhydride;...

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Product Details:

N-Boc-O-Benzyl-D-serine Basic information

Product Name:

N-Boc-O-Benzyl-D-serine

Synonyms:

(2R)-2-(tert-butoxycarbonylamino)-3-(phenylmethoxy)propanoic    acid;(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(phenylmethoxy)propanoic    acid;(2R)-2-[(tert-butoxy-oxomethyl)amino]-3-(phenylmethoxy)propanoic    acid;(2R)-3-(benzyloxy)-2-(tert-butoxycarbonylamino)propionic    acid;L-Serine,    N-((1,1-dimethylethoxy)carbonyl)-O-(phenylmethyl)-;Boc-D-Ser(Bzl)-OH, >=98%;O-Benzyl-N-(tert-butoxycarbonyl)-D-serine;Boc-O-benzyl-D-serine≥ 99.5% (HPLC)

CAS:

47173-80-8

MF:

C15H21NO5

MW:

295.33

EINECS:

245-820-1

Product Categories:

Amino    Acids;Boc-Amino    Acids and Derivative;Amino    Acids (N-Protected);Biochemistry;Boc-Amino Acids;Boc-Amino acid series

Mol File:

47173-80-8.mol

image001.gif


N-Boc-O-Benzyl-D-serine Chemical Properties

alpha 

-19 º (c=2 80% alcohol)

refractive index 

-20 ° (C=2, 80% EtOH)

form 

Powder

color 

White

Appearance:

White crystalline powder

Density:

1.174g/cm3

Melting   Point:

58-61ºC

Boiling   Point:

456.2ºC at 760mmHg

Flash    Point:

229.7ºC

Refractive Index:

-20 ° (C=2, 80% EtOH)

Storage   Condition:

2-8ºC

CAS DataBase Reference

47173-80-8(CAS    DataBase Reference)


Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

24/25-36-26

WGK Germany 

3

HazardClass 

IRRITANT

Hs code

2924299090


N-Boc-O-Benzyl-D-serine Usage And Synthesis

Chemical Properties

White crystalline powder

Intermediate as

159752-10-0 MK677(mesylate salt)    Ibutamoren

image003_副本.jpg

Reference:

Tetrahedron, , vol. 53, # 32 p. 10983 - 10992

Synthesis route

image005_副本.jpg

Reference:

Ramasamy, Kanda S.; Seifert, Wilfried    Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1519 - 1522
Qi, Xian Liang; Yang,    Er Qun; Zhang, Jun Tao; Wang, Tao; Cao, Xiao Ping Chinese Chemical Letters,    2012 , vol. 23, # 6 p. 661 - 664

image007_副本.jpg

Reference:

Qi, Xian Liang; Yang, Er Qun; Zhang, Jun Tao;    Wang, Tao; Cao, Xiao Ping Chinese Chemical Letters, 2012 , vol. 23, # 6 p.    661 - 664


N-Boc-O-Benzyl-D-serine Preparation Products And Raw materials


Upstream information

N-Boc-O-Benzyl-D-serine; tert-butoxycarbonyl anhydride; O-Benzyl-D-serine; BOC-L-Serine; benzyl bromide;


Downtream information

2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide; N-Boc-O-Benzyl-D-serine


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