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220210-56-0 3-tert-Butoxycarbonylphenylboronic Acid

220210-56-0 3-tert-Butoxycarbonylphenylboronic Acid

3-tert-Butoxycarbonylphenylboronic acid Basic information 3-tert-Butoxycarbonylphenylboronic acid Chemical Properties Safety Information 3-tert-Butoxycarbonylphenylboronic acid Usage And Synthesis Usage And Synthesis Upstream information 2-Bromo-3-methylpyridine; 3-t-Butoxycarbonylphenylboronic...

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Product Details:

3-tert-Butoxycarbonylphenylboronic acid Basic information

Product Name:

3-tert-Butoxycarbonylphenylboronic    acid

Synonyms:

3-(T-BUTOXYCARBONYL)PHENYLBORONIC    ACID; 3-(TERT-BUTOXYCARBONYL)BENZENEBORONIC    ACID; 3-(TERT-BUTOXYCARBONYL)PHENYLBORONIC    ACID; T-BUTYL 3-BORONOBENZOATE; 3-(Tert-Butoxycarbonyl)Phenylb; 3-(tert-Butoxycarbonyl)benzeneboronic    acid; 3-(T-BUTOXYCARBONYL)PHENYLBORBONIC    ACID; tert-Butyl 3-boronobenzoate

CAS:

220210-56-0

MF:

C11H15BO4

MW:

222.05

EINECS:

1806241-263-5

Product Categories:

blocks; Boronic Acids; Carboxes; Boronic    acids


3-tert-Butoxycarbonylphenylboronic acid Chemical Properties

Melting point 

96-102°C

storage temp. 

Keep Cold

CAS DataBase Reference

220210-56-0

Density:

1.15g/cm3

Melting    Point:

96-102ºC

Boiling    Point:

375ºC at 760mmHg

Flash Point:

180.6ºC

Refractive Index:

1.517

StorageCondition:

Keep Cold

Vapor   Pressure:

2.74E-06mmHg at 25°C


Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-60-37

Hazard Note 

Irritant/Keep Cold

HS    Code:

2931900090


3-tert-Butoxycarbonylphenylboronic acid Usage And Synthesis

Chemical Properties

White to light yellow crystal    powde


Usage And Synthesis


Uses

suzuki reaction

Intermediate as

936727-05-8 VX-809 (Lumacaftor) and    1160221-26-0 Lumacaftor HCl

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Synthesis route

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Upstream information

2-Bromo-3-methylpyridine; 3-t-Butoxycarbonylphenylboronic acid;


Downtream information

tert-butyl 3-(6-amino-3-methylpyridin-2-yl)benzoate; 3-[6-[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino]-3-methylpyridin-2-yl]benzoic acid,hydrochloride; tert-Butyl 3-(3-methylpyridin-2-yl)benzoate

 

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