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Hofmann Elimination

Lianyungang Klinechem Co.,Ltd | Updated: Dec 07, 2018

Hofmann Elimination

Sometimes referred to as the Hofmann Degradation. This elimination reaction of alkyl trimethyl amines proceeds with anti-stereochemistry, and is generally suitable for producing alkenes with one or two substituents. The reaction follows the Hofmann Rule.

Mechanism of the Hofmann Elimination

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