Lianyungang Klinechem Co.,Ltd
call us on: +86-518-88103268
Home > Knowledge > Content

Hunsdiecker Reaction

Lianyungang Klinechem Co.,Ltd | Updated: Dec 07, 2018

Hunsdiecker Reaction

The silver(I) salts of carboxylic acids react with halogens to give unstable intermediates which readily decarboxylate thermally to yield alkyl halides. The reaction is believed to involve homolysis of the C-C bond and a radical chain mechanism.

Mechanism of the Hunsdiecker Reaction

Recent Literature

Silver-Catalyzed Decarboxylative Bromination of Aliphatic Carboxylic Acids
X. Tan, T. Song, Z. Wang, H. Chen, L. Cui, C. Li, Org. Lett.201719, 1634-1637.

Silver-Catalyzed Decarboxylative Chlorination of Aliphatic Carboxylic Acids
Z. Wang, L. Zhu, F. Yin, Z. Su, Z. Li, C. Li, J. Am. Chem. Soc.2012134, 4258-4263.

Catalytic Hunsdiecker Reaction of α,β-Unsaturated Carboxylic Acids: How Efficient Is the Catalyst?
J. Prakash, S. Roy, J. Org. Chem.200267, 7861-7864.

Stereoselective Synthesis of (E)-β-Arylvinyl Bromides by Microwave-Induced Hunsdiecker-Type Reaction
C. Kuang, Q. Yang, H. Senboku, M. Tokuda, Synthesis2005, 1319-1325.

Contact Us
Address: Jingqi Road, Weiwu Road, Coastal Industrial Park, Guanyun County, Lianyungang City, Jiangsu Province

© Lianyungang Klinechem Co.,Ltd